THERAPEUTICAL PEPTIDOMIMETIC

The present invention relates to peptidomimetics of a short peptide from leucyl-tRNA synthetase, compositions comprising one or more of said peptidomimetics and their use for the treatment of syndromes caused by mutations of mt-tRNA (mitochondrial transfer RNA) genes, and medical treatments of said...

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Bibliographic Details
Main Authors MOREA, VERONICA, PISANO, ANNALINDA, D'AMATI, GIULIA, PIGNATARO, MARIA GEMMA, PERLI, ELENA
Format Patent
LanguageEnglish
French
Published 06.07.2023
Subjects
CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Summary:The present invention relates to peptidomimetics of a short peptide from leucyl-tRNA synthetase, compositions comprising one or more of said peptidomimetics and their use for the treatment of syndromes caused by mutations of mt-tRNA (mitochondrial transfer RNA) genes, and medical treatments of said syndromes comprising the administration of said one or more peptidomimetics or compositions comprising the same. La présente invention concerne des peptidomimétiques d'un peptide court à partir de leucyl-ARNt synthétase, des compositions comprenant un ou plusieurs desdits peptidomimétiques et leur utilisation pour le traitement de syndromes provoqués par des mutations des gènes de mt-ARNt (ARN de transfert mitochondrial), et des traitements médicaux desdits syndromes comprenant l'administration dudit ou desdits peptidomimétiques ou de compositions les comprenant.
Bibliography:Application Number: CA20223240978