CDK9 INHIBITOR AND USE THEREOF

The present invention relates to the field of medicines, specifically relates to a CDK9 inhibitor compound represented by formula (I), and a pharmaceutically acceptable salt or isomer thereof, and also relates to a pharmaceutical composition and pharmaceutical preparation of the compound and a use t...

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Bibliographic Details
Main Authors LI, LIN, MIYANO, NATSUMI, WU, FRANK, YOKOSAKA, TAKUYA, KAWASAKI, MASANORI, WANG, WUWEI
Format Patent
LanguageEnglish
French
Published 22.06.2023
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:The present invention relates to the field of medicines, specifically relates to a CDK9 inhibitor compound represented by formula (I), and a pharmaceutically acceptable salt or isomer thereof, and also relates to a pharmaceutical composition and pharmaceutical preparation of the compound and a use thereof. X1, X2, R1, R2, R3, R6, A, L, n, and m are as defined in the description. The compound can be used in the preparation of a drug for treating or preventing CDK9-mediated related diseases. La présente invention concerne le domaine des médicaments, spécifiquement un composé inhibiteur de CDK9 représenté par la formule (I), et un sel ou un isomère pharmaceutiquement acceptables de celui-ci, et concerne également une composition pharmaceutique et une préparation pharmaceutique du composé et une utilisation de celui-ci. X1, X2, R1, R2, R3, R6, A, L, n et m sont tels que définis dans la description. Le composé peut être utilisé dans la préparation d'un médicament pour le traitement ou la prévention de maladies associées à médiation par CDK9.
Bibliography:Application Number: CA20223240763