INHIBITORS OF HIF-2ALPHA AND METHODS OF USE THEREOF

The present disclosure is directed to compounds that are inhibitors of HIF-2? having a structure according to Formula I, and compositions containing those compounds. Methods of using the compounds for the treatment of diseases, disorders, or conditions are also described. La présente invention conce...

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Main Authors LIU, DONGDONG, YU, KAI, HARDMAN, CLAYTON, PODUNAVAC, MA?A, LAWSON, KENNETH VICTOR, EPPLIN, MATTHEW, BEATTY, JOEL WORLEY, DREW, SAMUEL LAWRIE, GAL, BALINT, POWERS, JAY PATRICK, LELETI, MANMOHAN REDDY, FOURNIER, JEREMY, MATA, GUILLAUME, ROSEN, BRANDON REID, MAILYAN, ARTUR KARENOVICH
Format Patent
LanguageEnglish
French
Published 04.05.2023
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Abstract The present disclosure is directed to compounds that are inhibitors of HIF-2? having a structure according to Formula I, and compositions containing those compounds. Methods of using the compounds for the treatment of diseases, disorders, or conditions are also described. La présente invention concerne des composés qui sont des inhibiteurs d'HIF-2? ayant une structure selon la formule I, et des compositions contenant ces composés. L'invention concerne également des procédés d'utilisation des composés pour le traitement de maladies, de troubles ou d'états pathologiques.
AbstractList The present disclosure is directed to compounds that are inhibitors of HIF-2? having a structure according to Formula I, and compositions containing those compounds. Methods of using the compounds for the treatment of diseases, disorders, or conditions are also described. La présente invention concerne des composés qui sont des inhibiteurs d'HIF-2? ayant une structure selon la formule I, et des compositions contenant ces composés. L'invention concerne également des procédés d'utilisation des composés pour le traitement de maladies, de troubles ou d'états pathologiques.
Author MAILYAN, ARTUR KARENOVICH
HARDMAN, CLAYTON
LELETI, MANMOHAN REDDY
FOURNIER, JEREMY
LAWSON, KENNETH VICTOR
POWERS, JAY PATRICK
YU, KAI
DREW, SAMUEL LAWRIE
BEATTY, JOEL WORLEY
EPPLIN, MATTHEW
PODUNAVAC, MA?A
ROSEN, BRANDON REID
MATA, GUILLAUME
LIU, DONGDONG
GAL, BALINT
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– fullname: EPPLIN, MATTHEW
– fullname: BEATTY, JOEL WORLEY
– fullname: DREW, SAMUEL LAWRIE
– fullname: GAL, BALINT
– fullname: POWERS, JAY PATRICK
– fullname: LELETI, MANMOHAN REDDY
– fullname: FOURNIER, JEREMY
– fullname: MATA, GUILLAUME
– fullname: ROSEN, BRANDON REID
– fullname: MAILYAN, ARTUR KARENOVICH
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Snippet The present disclosure is directed to compounds that are inhibitors of HIF-2? having a structure according to Formula I, and compositions containing those...
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HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
Title INHIBITORS OF HIF-2ALPHA AND METHODS OF USE THEREOF
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