INHIBITORS OF HIF-2ALPHA AND METHODS OF USE THEREOF

The present disclosure is directed to compounds that are inhibitors of HIF-2? having a structure according to Formula I, and compositions containing those compounds. Methods of using the compounds for the treatment of diseases, disorders, or conditions are also described. La présente invention conce...

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Main Authors LIU, DONGDONG, YU, KAI, HARDMAN, CLAYTON, PODUNAVAC, MA?A, LAWSON, KENNETH VICTOR, EPPLIN, MATTHEW, BEATTY, JOEL WORLEY, DREW, SAMUEL LAWRIE, GAL, BALINT, POWERS, JAY PATRICK, LELETI, MANMOHAN REDDY, FOURNIER, JEREMY, MATA, GUILLAUME, ROSEN, BRANDON REID, MAILYAN, ARTUR KARENOVICH
Format Patent
LanguageEnglish
French
Published 04.05.2023
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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Summary:The present disclosure is directed to compounds that are inhibitors of HIF-2? having a structure according to Formula I, and compositions containing those compounds. Methods of using the compounds for the treatment of diseases, disorders, or conditions are also described. La présente invention concerne des composés qui sont des inhibiteurs d'HIF-2? ayant une structure selon la formule I, et des compositions contenant ces composés. L'invention concerne également des procédés d'utilisation des composés pour le traitement de maladies, de troubles ou d'états pathologiques.
Bibliography:Application Number: CA20223236553