BICYCLIC HETEROCYCLIC FGFR4 INHIBITOR, PHARMACEUTICAL COMPOSITION AND PREPARATION, AND A USE THEREOF

Provided are a bicyclic heterocyclic FGFR4 inhibitor, a pharmaceutical composition and a preparation comprising same, and an application thereof. In particular, provided is a compound having a structure represented by formula (I), wherein the compound can be used as an FGFR4 inhibitor for preventing...

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Main Authors JIN, YAOFENG, LIANG, SAI, CHEN, WEILIANG, WANG, ZHANGUO, LV, JIANHUA, ZHU, FANGMENG, GUO, XUEJIE, ZHAN, WEIQIANG
Format Patent
LanguageEnglish
French
Published 29.09.2022
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:Provided are a bicyclic heterocyclic FGFR4 inhibitor, a pharmaceutical composition and a preparation comprising same, and an application thereof. In particular, provided is a compound having a structure represented by formula (I), wherein the compound can be used as an FGFR4 inhibitor for preventing and/or treating diseases mediated at least in part by FGFR4 (such as, cancer). L'invention concerne un inhibiteur de FGFR4 hétérocyclique bicyclique, une composition pharmaceutique, une préparation le comprenant, et une utilisation associée. En particulier, l'invention concerne un composé ayant une structure représentée par la formule (I), le composé pouvant être utilisé en tant qu'inhibiteur de FGFR4 pour prévenir et/ou traiter des maladies médiées au moins en partie par FGFR4 (comme le cancer).
Bibliography:Application Number: CA20213213379