NOVEL CYCLOPENTA[C]PYRROL NEGATIVE ALLOSTERIC MODULATORS OF NR2B

The present disclosure provides a compound of formula (I), or a pharmaceutically acceptable salt thereof; a method for manufacturing the compounds of the disclosure, and its therapeutic uses. The present disclosure further provides a combination of pharmacologically active agents and a pharmaceutica...

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Bibliographic Details
Main Authors GARDINIER, KEVIN MATTHEW, HEALY, MARK PATRICK, YANG, FAN, PAN, YUE, WANG, KATE YAPING, JENDZA, KEITH
Format Patent
LanguageEnglish
French
Published 29.09.2022
Subjects
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Summary:The present disclosure provides a compound of formula (I), or a pharmaceutically acceptable salt thereof; a method for manufacturing the compounds of the disclosure, and its therapeutic uses. The present disclosure further provides a combination of pharmacologically active agents and a pharmaceutical composition. La présente divulgation concerne un composé de formule (I), ou un sel pharmaceutiquement acceptable de celui-ci; un procédé de fabrication des composés de l'invention et leurs utilisations thérapeutiques. La présente divulgation concerne en outre une combinaison d'agents pharmacologiquement actifs et une composition pharmaceutique.
Bibliography:Application Number: CA20223212203