3H,4H-THIENO[2,3-D]PYRIMIDIN-4-ONE DERIVATIVES AS TRPA1 INHIBITORS

The present disclosure provides certain 3H,4H-thieno[2,3-d]pyrimidin-4-one derivatives that are inhibitors of transient receptor potential ankyrin 1 (TRPA1), and are therefore useful for the treatment of diseases treatable by inhibition of TRPA1. Also provided are pharmaceutical compositions contain...

Full description

Saved in:
Bibliographic Details
Main Authors WILLWACHER, JENS, BINDER, FLORIAN PAUL CHRISTIAN, FLECK, MARTIN THOMAS
Format Patent
LanguageEnglish
French
Published 20.10.2022
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
Online AccessGet full text

Cover

More Information
Summary:The present disclosure provides certain 3H,4H-thieno[2,3-d]pyrimidin-4-one derivatives that are inhibitors of transient receptor potential ankyrin 1 (TRPA1), and are therefore useful for the treatment of diseases treatable by inhibition of TRPA1. Also provided are pharmaceutical compositions containing the same, and processes for preparing said compounds. La présente invention concerne certains dérivés de 3H, 4H-thiéno [2,3-d] pyrimidin-4-one qui sont des inhibiteurs de potentiel de récepteur transitoire ankyrine 1 (TRPA1), et sont par conséquent utiles pour le traitement de maladies pouvant être traitées par inhibition de TRPA1. L'invention concerne également des compositions pharmaceutiques les contenant, et des procédés de préparation desdits composés.
Bibliography:Application Number: CA20223210965