E. COLI FIMH MUTANTS AND USES THEREOF

This disclosure relates to the design of E. coli mutated FimH polypeptides that result in improved biochemical properties and immunogenicity, compositions comprising such polypeptides, and uses thereof. La présente invention concerne la conception de polypeptides FimH mutés E. COLI qui conduisent à...

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Bibliographic Details
Main Authors SILMON DE MONERRI, NATALIE CLARE, CHE, YE, CHORRO, LAURENT OLIVER, GRIFFOR, MATTHEW CURTIS, DONALD, ROBERT GEORGE KONRAD
Format Patent
LanguageEnglish
French
Published 30.06.2022
Subjects
CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Summary:This disclosure relates to the design of E. coli mutated FimH polypeptides that result in improved biochemical properties and immunogenicity, compositions comprising such polypeptides, and uses thereof. La présente invention concerne la conception de polypeptides FimH mutés E. COLI qui conduisent à des propriétés biochimiques et à une immunogénicité améliorées, des compositions comprenant de tels polypeptides, et leurs utilisations.
Bibliography:Application Number: CA20213205927