MODIFIED MIR-135, CONJUGATED FORM THEREOF, AND USES OF SAME
A composition of matter comprising a synthetic miR-135 molecule comprising a nucleic acid sequence of a miR-135b as set forth in SEQ ID NO: 37, and a complementary strand as set forth in SEQ ID NO: 40 is disclosed. A conjugate comprising a composition of matter comprising a synthetic miR-135 molecul...
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Format | Patent |
Language | English French |
Published |
21.07.2022
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Abstract | A composition of matter comprising a synthetic miR-135 molecule comprising a nucleic acid sequence of a miR-135b as set forth in SEQ ID NO: 37, and a complementary strand as set forth in SEQ ID NO: 40 is disclosed. A conjugate comprising a composition of matter comprising a synthetic miR-135 molecule and a cell-targeting moiety is also disclosed.
L'invention concerne une composition de matière comprenant une molécule de miR-135 synthétique comprenant une séquence d'acide nucléique d'un miR-135b tel que défini dans SEQ ID NO : 37, et un brin complémentaire tel que défini dans SEQ ID NO : 40. L'invention concerne également un conjugué comprenant une composition de matière comprenant une molécule de miR -135 synthétique et une fraction de ciblage de cellule. |
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AbstractList | A composition of matter comprising a synthetic miR-135 molecule comprising a nucleic acid sequence of a miR-135b as set forth in SEQ ID NO: 37, and a complementary strand as set forth in SEQ ID NO: 40 is disclosed. A conjugate comprising a composition of matter comprising a synthetic miR-135 molecule and a cell-targeting moiety is also disclosed.
L'invention concerne une composition de matière comprenant une molécule de miR-135 synthétique comprenant une séquence d'acide nucléique d'un miR-135b tel que défini dans SEQ ID NO : 37, et un brin complémentaire tel que défini dans SEQ ID NO : 40. L'invention concerne également un conjugué comprenant une composition de matière comprenant une molécule de miR -135 synthétique et une fraction de ciblage de cellule. |
Author | CHEN, ALON MANASHIROV, SHARON MONTEFELTRO, ANDRES PABLO |
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DocumentTitleAlternate | MIR-135 MODIFIE, FORME CONJUGUEE DE CELUI-CI, ET SES UTILISATIONS |
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Snippet | A composition of matter comprising a synthetic miR-135 molecule comprising a nucleic acid sequence of a miR-135b as set forth in SEQ ID NO: 37, and a... |
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SubjectTerms | BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SPIRITS VINEGAR WINE |
Title | MODIFIED MIR-135, CONJUGATED FORM THEREOF, AND USES OF SAME |
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