MODIFIED MIR-135, CONJUGATED FORM THEREOF, AND USES OF SAME

A composition of matter comprising a synthetic miR-135 molecule comprising a nucleic acid sequence of a miR-135b as set forth in SEQ ID NO: 37, and a complementary strand as set forth in SEQ ID NO: 40 is disclosed. A conjugate comprising a composition of matter comprising a synthetic miR-135 molecul...

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Bibliographic Details
Main Authors MONTEFELTRO, ANDRES PABLO, CHEN, ALON, MANASHIROV, SHARON
Format Patent
LanguageEnglish
French
Published 21.07.2022
Subjects
BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS THEREOF
CULTURE MEDIA
ENZYMOLOGY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
SPIRITS
VINEGAR
WINE
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Summary:A composition of matter comprising a synthetic miR-135 molecule comprising a nucleic acid sequence of a miR-135b as set forth in SEQ ID NO: 37, and a complementary strand as set forth in SEQ ID NO: 40 is disclosed. A conjugate comprising a composition of matter comprising a synthetic miR-135 molecule and a cell-targeting moiety is also disclosed. L'invention concerne une composition de matière comprenant une molécule de miR-135 synthétique comprenant une séquence d'acide nucléique d'un miR-135b tel que défini dans SEQ ID NO : 37, et un brin complémentaire tel que défini dans SEQ ID NO : 40. L'invention concerne également un conjugué comprenant une composition de matière comprenant une molécule de miR -135 synthétique et une fraction de ciblage de cellule.
Bibliography:Application Number: CA20223204415