ANTIBODY COMPOSITIONS AND METHODS OF USE THEREOF

The disclosure provides pharmaceutical compositions comprising an antibody and at least two antioxidants. In some aspects, pharmaceutical composition is formulated for subcutaneous delivery. In some aspects, the pharmaceutical composition further comprises an endoglycosidase hydrolase enzyme. Other...

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Main Authors ZHAO, XIAOCHEN, HABY, THOMAS ARTHUR, KHOSSRAVI, MEHRNAZ, ROY, AMIT, MURTHY, BINDU PURNIMA, ARAS, URVI ASHISH, MANTRI, RAO VENKATRAMANA, VEZINA, HEATHER ELIZABETH, HUANG, MASANO, SANGHAVI, KINJAL, HART, SCOTT AARON, BELLO, AKINTUNDE
Format Patent
LanguageEnglish
French
Published 07.07.2022
Subjects
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:The disclosure provides pharmaceutical compositions comprising an antibody and at least two antioxidants. In some aspects, pharmaceutical composition is formulated for subcutaneous delivery. In some aspects, the pharmaceutical composition further comprises an endoglycosidase hydrolase enzyme. Other aspects of the present disclosure are directed to methods of subcutaneously delivering the pharmaceutical composition. L'invention concerne des compositions pharmaceutiques comprenant un anticorps et au moins deux antioxydants. Dans certains aspects, la composition pharmaceutique est formulée pour une administration sous-cutanée. Dans certains aspects, la composition pharmaceutique comprend en outre une enzyme endoglycosidase hydrolase. D'autres aspects de la présente invention concernent des méthodes d'administration sous-cutanée de la composition pharmaceutique.
Bibliography:Application Number: CA20213201348