TREATMENT OF NSCLC PATIENTS WITH TUMOR INFILTRATING LYMPHOCYTE THERAPIES
The present invention provides improved and/or shortened processes and methods for preparing TILs in order to prepare therapeutic populations of TILs with increased therapeutic efficacy for the treatment of non-small cell lung carcinoma (NSCLC), wherein the NSCLC is refractory to treatment with an a...
Saved in:
| Main Authors | , |
|---|---|
| Format | Patent |
| Language | English French |
| Published |
14.04.2022
|
| Subjects | |
| Online Access | Get full text |
Cover
Loading…
| Abstract | The present invention provides improved and/or shortened processes and methods for preparing TILs in order to prepare therapeutic populations of TILs with increased therapeutic efficacy for the treatment of non-small cell lung carcinoma (NSCLC), wherein the NSCLC is refractory to treatment with an anti -PD- 1 antibody and/or anti-PD-Ll antibody and/or VEGF inhibitor, or wherein the NSCLC has a predetermined tumor proportion score (TPS).
La présente invention concerne des méthodes et des processus améliorés et/ou abrégés pour préparer des TIL afin de préparer des populations thérapeutiques de TIL avec une efficacité thérapeutique accrue pour le traitement du carcinome pulmonaire non à petites cellules (CPNPC), le CPNPCétant réfractaire au traitement avec un anticorps anti-PD-1 et/ou un anticorps anti-PD-Ll et/ou un inhibiteur de VEGF, ou le CPNPC ayant un score de proportion tumorale (TPS) prédéterminé. |
|---|---|
| AbstractList | The present invention provides improved and/or shortened processes and methods for preparing TILs in order to prepare therapeutic populations of TILs with increased therapeutic efficacy for the treatment of non-small cell lung carcinoma (NSCLC), wherein the NSCLC is refractory to treatment with an anti -PD- 1 antibody and/or anti-PD-Ll antibody and/or VEGF inhibitor, or wherein the NSCLC has a predetermined tumor proportion score (TPS).
La présente invention concerne des méthodes et des processus améliorés et/ou abrégés pour préparer des TIL afin de préparer des populations thérapeutiques de TIL avec une efficacité thérapeutique accrue pour le traitement du carcinome pulmonaire non à petites cellules (CPNPC), le CPNPCétant réfractaire au traitement avec un anticorps anti-PD-1 et/ou un anticorps anti-PD-Ll et/ou un inhibiteur de VEGF, ou le CPNPC ayant un score de proportion tumorale (TPS) prédéterminé. |
| Author | FINCKENSTEIN, FRIEDRICH GRAF FARDIS, MARIA |
| Author_xml | – fullname: FARDIS, MARIA – fullname: FINCKENSTEIN, FRIEDRICH GRAF |
| BookMark | eNrjYmDJy89L5WTwCAlydQzxdfULUfB3U_ALdvZxVghwDPEECgQrhHuGeCiEhPr6Byl4-rl5-oQEAWX83BV8In0DPPydI0NcFUI8XIMcAzxdg3kYWNMSc4pTeaE0N4OCm2uIs4duakF-fGpxQWJyal5qSbyzo7GhpamBoaWjoTERSgAIDy6g |
| ContentType | Patent |
| DBID | EVB |
| DatabaseName | esp@cenet |
| DatabaseTitleList | |
| Database_xml | – sequence: 1 dbid: EVB name: esp@cenet url: http://worldwide.espacenet.com/singleLineSearch?locale=en_EP sourceTypes: Open Access Repository |
| DeliveryMethod | fulltext_linktorsrc |
| Discipline | Medicine Chemistry Sciences |
| DocumentTitleAlternate | TRAITEMENT DE PATIENTS SOUFFRANT DE CPNPC AVEC DES THERAPIES DE LYMPHOCYTES INFILTRANT LES TUMEURS |
| ExternalDocumentID | CA3195019A1 |
| GroupedDBID | EVB |
| ID | FETCH-epo_espacenet_CA3195019A13 |
| IEDL.DBID | EVB |
| IngestDate | Fri Aug 30 05:41:42 EDT 2024 |
| IsOpenAccess | true |
| IsPeerReviewed | false |
| IsScholarly | false |
| Language | English French |
| LinkModel | DirectLink |
| MergedId | FETCHMERGED-epo_espacenet_CA3195019A13 |
| Notes | Application Number: CA20213195019 |
| OpenAccessLink | https://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20220414&DB=EPODOC&CC=CA&NR=3195019A1 |
| ParticipantIDs | epo_espacenet_CA3195019A1 |
| PublicationCentury | 2000 |
| PublicationDate | 20220414 |
| PublicationDateYYYYMMDD | 2022-04-14 |
| PublicationDate_xml | – month: 04 year: 2022 text: 20220414 day: 14 |
| PublicationDecade | 2020 |
| PublicationYear | 2022 |
| RelatedCompanies | IOVANCE BIOTHERAPEUTICS, INC |
| RelatedCompanies_xml | – name: IOVANCE BIOTHERAPEUTICS, INC |
| Score | 3.3876486 |
| Snippet | The present invention provides improved and/or shortened processes and methods for preparing TILs in order to prepare therapeutic populations of TILs with... |
| SourceID | epo |
| SourceType | Open Access Repository |
| SubjectTerms | HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES |
| Title | TREATMENT OF NSCLC PATIENTS WITH TUMOR INFILTRATING LYMPHOCYTE THERAPIES |
| URI | https://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20220414&DB=EPODOC&locale=&CC=CA&NR=3195019A1 |
| hasFullText | 1 |
| inHoldings | 1 |
| isFullTextHit | |
| isPrint | |
| link | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwfV3NT8IwFH8haNSbokbwIz2Y3RYp6xg9LGZ0m5thHxlF4US2wRIug8iM_77tAuhFb81r8vLa5PV99f0ewKMc3bDo51ilekZVohtYTYtUhCoDQytoN9e6NXZnEPa9CXmd6tMGrPa9MDVO6FcNjig0Khf6XtXv9eYniWXXfyu3T9lKkNbPLjdtZRcd93pdgoliD00njuyIKYyZzFLCxNTkuFNMLREoHUkvWsLsO29D2ZSy-W1R3HM4jgWzsrqAxrJswSnbD15rwUmwq3eL5U71tpfg8cSxuITeR5GLwjEbMRRb3BeEMXr3uYf4JIgS5IeuP-Iy9RS-oNEsiL2IzbiDuOckViycvytArsOZpwqR5ofjz5l1EF67hma5Lpc3gPokN0ihZXkhHDhKSYYLmhqDVMcLPMg13Ib2n2w6_-zdwpm8R1kwweQOmtXH5_Je2N0qe6hv7BulIYA3 |
| link.rule.ids | 230,309,786,891,25594,76906 |
| linkProvider | European Patent Office |
| linkToHtml | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwfV1LT8JAEJ4QNOJNUSM-92B6a2TpltJDY8q2tdW-UhaFE2kLTbgUIjX-fXcbQC9628wmk9lNZue18w3AgxjdMO_nWNbVTJeJqmE5LVIeqgw0pdC7udKtsTuDsO-OyctEnTRgueuFqXFCv2pwRK5ROdf3qn6v1z9JLKv-W7l5zJactHpymGFJ2-i41-sSTCRraNhxZEVUotSgphQmhiLGnWLd5IHSgSbAeYXn9DYUTSnr3xbFOYHDmDMrq1NoLMo2tOhu8FobjoJtvZsvt6q3OQOXJbbJBPQ-ihwUjqhPUWwyjxNG6N1jLmLjIEqQFzqez0TqKXxG_jSI3YhOmY2YaydmzJ2_c0COzagrc5Fm--PPqLkXXrmAZrkqF5eA-iTXSKFkecEdOF0nGS70VBukKp7jQa7gDnT-ZHP1z949tFwW-DPfC1-v4VjcqSieYHIDzerjc3HLbXCV3dW39w3MxoMk |
| openUrl | ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Apatent&rft.title=TREATMENT+OF+NSCLC+PATIENTS+WITH+TUMOR+INFILTRATING+LYMPHOCYTE+THERAPIES&rft.inventor=FARDIS%2C+MARIA&rft.inventor=FINCKENSTEIN%2C+FRIEDRICH+GRAF&rft.date=2022-04-14&rft.externalDBID=A1&rft.externalDocID=CA3195019A1 |