NEW COMPOUNDS

The invention relates to novel compounds for use as inhibitors of NLRP3 inflammasone production, wherein such compounds are as defined by compounds of formula (I) and wherein the integers R1, R2 and R3 are defined in the description, and where the compounds may be useful as medicaments, for instance...

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Bibliographic Details
Main Authors VAN ROMPAEYIES, OEHLRICH, DANIEL, LAMKANFI, MOHAMED, VAN OPDENBOSCH, NINA, TRESADERN, GARY JOHN, LLAVERIA CROS, JOSEP, VAN GOOL, MICHIEL LUC MARIA
Format Patent
LanguageEnglish
French
Published 31.03.2022
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:The invention relates to novel compounds for use as inhibitors of NLRP3 inflammasone production, wherein such compounds are as defined by compounds of formula (I) and wherein the integers R1, R2 and R3 are defined in the description, and where the compounds may be useful as medicaments, for instance for use in the treatment of a disease or disorder that is associated with NLRP3 inflammasome activity. L'invention concerne de nouveaux composés destinés à être utilisés comme inhibiteurs de la production d'inflammasomes NLRP3, lesdits composés étant tels que définis par les composés de formule (I) et les entiers R1, R2 et R3 étant tels que définis dans la description, lesdits composés étant utilisables comme médicaments, par exemple, pour le traitement d'une maladie ou d'un trouble qui est associé(e) à l'activité de l'inflammasome NLRP3.
Bibliography:Application Number: CA20213189887