ANTI-PVRIG PROTEIN ANTIBODY OR ANTIBODY FRAGMENT AND USE THEREOF

Provided is an antibody or antibody fragment. The antibody or the antibody fragment includes HCDR1 selected from GYTFSSFS, GYTFSTFA, or GYSFTAYT, HCDR2 selected from ILPGSNST, ILPGINNT, ILPGGNNT, or INPYNGGT, and HCDR3 selected from SSYWFAY, STYWFAY, or AREGNYYGSRGDFDY; and LCDR1 selected from QSLLN...

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Bibliographic Details
Main Authors LI, YANGYANG, SUN, HAOYU, XIAO, WEIHUA, SUN, RUI, TIAN, ZHIGANG
Format Patent
LanguageEnglish
French
Published 15.09.2022
Subjects
CHEMISTRY
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
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Summary:Provided is an antibody or antibody fragment. The antibody or the antibody fragment includes HCDR1 selected from GYTFSSFS, GYTFSTFA, or GYSFTAYT, HCDR2 selected from ILPGSNST, ILPGINNT, ILPGGNNT, or INPYNGGT, and HCDR3 selected from SSYWFAY, STYWFAY, or AREGNYYGSRGDFDY; and LCDR1 selected from QSLLNSGNQKNY or QTIVTN, LCDR2 selected from GAS or YAS, and LCDR3 selected from QNAHSYPPT, QNAHSYPPA, or QQSHSWPFT. The provided antibody can be used for treating cancer. L'invention concerne un anticorps ou un fragment d'anticorps. L'anticorps ou le fragment d'anticorps comprend HCDR1 choisi parmi GYTFSSFS, GYTFSTFA ou GYSFTAYT, HCDR2 choisi parmi ILPGSNST, ILPGINNT, ILPGGNNT ou INPYNGGT, et HCDR3 choisi parmi SSYWFAY, STYWFAY ou AREGNYYGSRGDFDY; et LCDR1 choisi parmi QSLLNSGNQKNY ou QTIVTN, LCDR2 choisi parmi GAS ou YAS, et LCDR3 choisi parmi QNAHSYPPT, QNAHSYPPA ou QQSHSWPFT. L'anticorps selon l'invention peut être utilisé pour traiter un cancer.
Bibliography:Application Number: CA20223189496