MACROPHAGE TARGETING DRUG CONJUGATES

Described herein are novel, macrophage targeting drug conjugates. The macrophage targeting drug conjugates comprise a drug moiety, a mannose moiety, and a linker connecting the drug moiety and the mannose moiety. The linker may comprise a hydrazone group or an oxime group. L'invention concerne...

Full description

Saved in:
Bibliographic Details
Main Authors GOLDBERG, ISAIAH Z, GOLDBERG, JAMES I, GOLDBERG, MICHAEL M, GOLDBERG, ALEC M, GOLDBERG, SAMUEL H
Format Patent
LanguageEnglish
French
Published 17.02.2022
Subjects
CHEMISTRY
DERIVATIVES THEREOF
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
NUCLEIC ACIDS
NUCLEOSIDES
NUCLEOTIDES
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
SUGARS
Online AccessGet full text

Cover

More Information
Summary:Described herein are novel, macrophage targeting drug conjugates. The macrophage targeting drug conjugates comprise a drug moiety, a mannose moiety, and a linker connecting the drug moiety and the mannose moiety. The linker may comprise a hydrazone group or an oxime group. L'invention concerne de nouveaux conjugués de médicament ciblant des macrophages. Les conjugués de médicament ciblant les macrophages comprennent une fraction de médicament, une fraction de mannose et un lieur reliant la fraction de médicament et la fraction de mannose. Le lieur peut comprendre un groupe hydrazone ou un groupe oxime.
Bibliography:Application Number: CA20213187751