PHARMACEUTICAL COMPOSITIONS COMPRISING (S)-4-(4-(4-(((2-(2,6-DIOXOPIPERIDIN-3-YL)-1-OXOISOINDOLIN-4-YL)OXY)M ETHYL) BENZYL)PIPERAZIN-1-YL)-3-FLUOROBENZONITRILE AND METHODS OF USING THE SAM
Provided herein are pharmaceutical compositions (e.g., oral dosage formulations) comprising (S)-4-(4-(4-(((2-(2,6-dioxopiperidin-3-yl)-l-oxoisoindolin-4- yl)oxy)methyl)benzyl)piperazin-l-yl)-3-fluorobenzonitrile, or an enantiomer, mixture of enantiomers, tautomer, isotopolog, or pharmaceutically acc...
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Main Authors | , , , , , |
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Format | Patent |
Language | English French |
Published |
13.01.2022
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Subjects | |
Online Access | Get full text |
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Summary: | Provided herein are pharmaceutical compositions (e.g., oral dosage formulations) comprising (S)-4-(4-(4-(((2-(2,6-dioxopiperidin-3-yl)-l-oxoisoindolin-4- yl)oxy)methyl)benzyl)piperazin-l-yl)-3-fluorobenzonitrile, or an enantiomer, mixture of enantiomers, tautomer, isotopolog, or pharmaceutically acceptable salt thereof, and a carrier or diluent. Also provided herein are methods of preparing and methods of using the pharmaceutical compositions.
La présente invention concerne des compositions pharmaceutiques (par exemple, des formulations posologiques orales) comprenant du (S)-4-(4-(4-(((2-(2,6-dioxopipéridin-3-yl)-1-oxoisoindolin-4-yl)oxy)méthyl)benzyl)pipérazin-1-yl)-3-fluorobenzonitrile, ou un énantiomère, un mélange d'énantiomères, un tautomère, un isotopologue ou un sel pharmaceutiquement acceptable correspondant, et un support ou un diluant. L'invention concerne également des procédés de préparation et des méthodes d'utilisation des compositions pharmaceutiques. |
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Bibliography: | Application Number: CA20213184460 |