PROCESS FOR THE PREPARATION OF A CHIRAL PIPERAZINE-2-CARBOXYLIC ACID
The invention relates to a novel process for the preparation of a chiral piperazine-2- carboxylic acid or of a salt thereof of the formula (I). The chiral piperazine-2-carboxylic acid derivatives of the formula (I) are key intermediates for the preparation of fused heteroaryl dihydro pyrimidines whi...
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Main Authors | , , , , , , , , |
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Format | Patent |
Language | English French |
Published |
04.11.2021
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Subjects | |
Online Access | Get full text |
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Summary: | The invention relates to a novel process for the preparation of a chiral piperazine-2- carboxylic acid or of a salt thereof of the formula (I). The chiral piperazine-2-carboxylic acid derivatives of the formula (I) are key intermediates for the preparation of fused heteroaryl dihydro pyrimidines which are useful for the treatment and prophylaxis of hepatitis B virus infections.
La présente invention concerne un nouveau procédé de préparation d'un acide pipérazine-2-carboxylique chiral ou d'un sel de celui-ci de formule (I). Les dérivés d'acide pipérazine-2-carboxylique chiral de formule (I) sont des intermédiaires clés pour la préparation d'hétéroaryl-dihydropyrimidines fusionnées qui sont utiles pour le traitement et la prophylaxie d'infections par le virus de l'hépatite B. |
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Bibliography: | Application Number: CA20213179165 |