OPTIMIZED NUCLEOTIDE SEQUENCES ENCODING SARS-COV-2 ANTIGENS

The present invention relates to optimized nucleotide sequence encoding SARS-CoV-2 antigens. These sequences are particularly suitable for use in vaccine compositions for the treatment or prevention of infections caused by a ?-coronaviruses, including COVID-19 infections, in a human or animal subjec...

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Main Authors CHIVUKULA, SUDHA, DIAS, ANUSHA, KARVE, SHRIRANG, CASIMIRO, DANILO, FU, TONG-MING, PLITNIK, TIMOTHY, BOEGLIN, LIANNE, DUBINS, JEFFREY S, TRAN, KHANG ANH, KALNIN, KIRILL, DEROSA, FRANK, ZACHARIA, MINNIE, SKALESKI, JOSEPH A, GU, XIAOBO
Format Patent
LanguageEnglish
French
Published 11.11.2021
Subjects
CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:The present invention relates to optimized nucleotide sequence encoding SARS-CoV-2 antigens. These sequences are particularly suitable for use in vaccine compositions for the treatment or prevention of infections caused by a ?-coronaviruses, including COVID-19 infections, in a human or animal subject in need of such treatment. La présente invention se rapporte à une séquence nucléotidique optimisée codant pour des antigènes du SARS-CoV-2. Ces séquences sont particulièrement appropriées pour être utilisées dans des compositions de vaccin pour le traitement ou la prévention d'infections provoquées par des ?-coronavirus, y compris des infections par la COVID-19, chez un sujet humain ou un animal ayant besoin d'un tel traitement.
Bibliography:Application Number: CA20213177940