HUMANIZED, MOUSE OR CHIMERIC ANTI-CD47 MONOCLONAL ANTIBODIES

Humanized, mouse or chimeric anti-CD47 monoclonal antibodies are provided. The antibodies bind to human glycosylated and deglycosylated CD47 with an optimized Koff value, they disrupt the human CD47-SIRPa interaction, and find use in various therapeutic, preventive or diagnostic methods. The inventi...

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Bibliographic Details
Main Authors CHALONS-COTTAVOZ, MARIE, FALLOT, STEPHANIE, LAHMAR, MEHDI, GARRONE, PIERRE, BELTRAMINELLI, NICOLA, SCHWAMBORN, KLAUS
Format Patent
LanguageEnglish
French
Published 20.07.2017
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