BISPECIFIC APTAMER COMPOSITIONS FOR THE TREATMENT OF RETINAL DISORDERS

Disclosed herein are bispecific aptamers having affinity for multiple ligands and in particular, VEGF, IL8 and Ang2, as well as pharmaceutical compositions comprising the same. Methods of using some bispecific aptamers for the treatment of retinal diseases and disorders are also disclosed, as well a...

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Bibliographic Details
Main Authors QUICK, RYAN, LEVY, MATTHEW
Format Patent
LanguageEnglish
French
Published 14.10.2021
Subjects
BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS THEREOF
CULTURE MEDIA
ENZYMOLOGY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
SPIRITS
VINEGAR
WINE
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Summary:Disclosed herein are bispecific aptamers having affinity for multiple ligands and in particular, VEGF, IL8 and Ang2, as well as pharmaceutical compositions comprising the same. Methods of using some bispecific aptamers for the treatment of retinal diseases and disorders are also disclosed, as well as methods of making such bispecific aptamers and compositions. L'invention concerne des aptamères bispécifiques ayant une affinité pour de multiples ligands et en particulier, VEGF, IL8 et Ang2, ainsi que des compositions pharmaceutiques les comprenant. L'invention concerne également des procédés d'utilisation de certains aptamères bispécifiques pour le traitement de maladies et de troubles rétiniens, ainsi que des procédés de fabrication de tels aptamères et compositions bispécifiques.
Bibliography:Application Number: CA20213174984