ANTI-CERAMIDE ANTIBODIES

The present disclosure provides compositions of anti-ceramide antibodies and antigen-binding fragments thereof. The disclosure further provides methods of preventing or inhibiting cell death in a subject in need thereof comprising administering the anti-ceramide antibodies or antigen-binding fragmen...

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Bibliographic Details
Main Authors KOLESNICK, RICHARD, WANG, JORDON KUO-MING, LEVY, RAPHAEL, WU, YINAN, WANG, YONG, TINKELENBERG, ARTHUR
Format Patent
LanguageEnglish
French
Published 23.09.2021
Subjects
CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:The present disclosure provides compositions of anti-ceramide antibodies and antigen-binding fragments thereof. The disclosure further provides methods of preventing or inhibiting cell death in a subject in need thereof comprising administering the anti-ceramide antibodies or antigen-binding fragments to a subject. The subject in need thereof may suffer from an autoimmune disease, GI syndrome, or GvHD. La présente invention concerne des compositions d'anticorps anti-céramide et des fragments de liaison à l'antigène de ceux-ci. L'invention concerne en outre des procédés de prévention ou d'inhibition de la mort cellulaire chez un sujet en ayant besoin, comprenant l'administration des anticorps anti-céramide ou des fragments de liaison à l'antigène à un sujet. Le sujet qui en a besoin peut souffrir d'Une maladie auto-Immune, du syndrome gastro-intestinal ou du GvHD.
Bibliography:Application Number: CA20213172201