TETRAHYDROBENZO-QUINOLINE SULFONAMIDES DERIVATIVE COMPOUNDS

The present invention relates to tetrahydrobenzo-isoquinoline sulfonamides derivatives of formula (I), processes for preparing them, pharmaceutical compositions containing them and their use in treating disorders caused by IgE (such as allergic responses, non-allergic mast cell responses or certain...

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Bibliographic Details
Main Authors PHILPS, OLIVER, HEER, JAG PAUL, TRANI, GIANCARLO, NORMAN, TIMOTHY JOHN, HASLETT, GREGORY WILLIAM
Format Patent
LanguageEnglish
French
Published 01.07.2021
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:The present invention relates to tetrahydrobenzo-isoquinoline sulfonamides derivatives of formula (I), processes for preparing them, pharmaceutical compositions containing them and their use in treating disorders caused by IgE (such as allergic responses, non-allergic mast cell responses or certain autoimmune responses), and in particular disorders caused by the interaction of IgE with the FceRI receptor. La présente invention concerne des dérivés de tétrahydrobenzo-isoquinoléine sulfonamides de formule (I), des procédés pour les préparer, des compositions pharmaceutiques les contenant et leur utilisation dans le traitement de troubles provoqués par IgE (tels que des réponses allergiques, des réponses de mastocytes non allergiques ou certaines réponses auto-immunes), et en particulier de troubles provoqués par l'interaction d'IgE avec le récepteur de FceRI.
Bibliography:Application Number: CA20203163920