THERAPEUTIC COMPOUNDS FOR METHODS OF USE IN INSULIN RESISTANCE

Embodiments of the disclosure encompass methods of treating insulin resistance in an individual in need thereof by administering one or more STAT3 inhibitors to the individual. In specific aspects, the methods allow for reversing insulin resistance in individuals. The STAT3 inhibitor may be one or m...

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Bibliographic Details
Main Authors MITCH, WILLIAM E, DE ACHAVAL, SOFIA, ALIBHAI, IMRAN, ZHANG, LIPING, TWEARDY, DAVID J
Format Patent
LanguageEnglish
French
Published 10.06.2021
Subjects
BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS THEREOF
CULTURE MEDIA
ENZYMOLOGY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
SPIRITS
VINEGAR
WINE
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Summary:Embodiments of the disclosure encompass methods of treating insulin resistance in an individual in need thereof by administering one or more STAT3 inhibitors to the individual. In specific aspects, the methods allow for reversing insulin resistance in individuals. The STAT3 inhibitor may be one or more particular small molecules encompassed herein. Des modes de réalisation de la divulgation concernent des méthodes de traitement de la résistance à l'insuline chez un individu en ayant besoin par l'administration d'un ou plusieurs inhibiteurs de STAT3 à l'individu. Dans des aspects spécifiques, les méthodes permettent d'inverser la résistance à l'insuline chez des individus. L'inhibiteur de STAT3 peut être une ou plusieurs petites molécules particulières englobées dans la description.
Bibliography:Application Number: CA20203163745