PHARMACEUTICAL COMPOSITIONS COMPRISING N-[1-(5-CYANO-PYRIDIN-2-YLMETHYL)-1H-PYRAZOL-3-YL]-2-[4-(1-TRIFLUOROMETHYL-CYCLOPROPYL)-PHENYL]-ACETAMIDE

The present invention relates to solid pharmaceutical compositions comprising N-[1-(5-cyano-pyridin-2- ylmethyl)-1H-pyrazol-3-yl]-2-[4-(1-trifluoromethyl-cyclopropyl)-phenyl]-acetamide or pharmaceutically acceptable salt thereof. The invention further relates to methods for manufacturing said compos...

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Bibliographic Details
Main Authors ELBAZ, FRANTZ, HEYER, FREDERIC, SOW, IBRAHIMA, AMBUEHL, MICHAEL, BENNIOU, NASSER
Format Patent
LanguageEnglish
French
Published 24.06.2021
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:The present invention relates to solid pharmaceutical compositions comprising N-[1-(5-cyano-pyridin-2- ylmethyl)-1H-pyrazol-3-yl]-2-[4-(1-trifluoromethyl-cyclopropyl)-phenyl]-acetamide or pharmaceutically acceptable salt thereof. The invention further relates to methods for manufacturing said compositions and their uses for the treatment or prevention of diseases and disorders linked to T-type calcium channels such as epilepsy. La présente invention concerne des compositions pharmaceutiques solides comprenant du N-[1-(5-cyano-pyridin-2-ylméthyl)-1H-pyrazol-3-yl]-2-[4-(1-trifluorométhyl-cyclopropyl)-phényl]-acétamide ou un sel pharmaceutiquement acceptable de celui-ci. L'invention concerne en outre des procédés de fabrication desdites compositions et leurs utilisations pour le traitement ou la prévention de maladies et de troubles liés à des canaux calciques de type T tels que l'épilepsie.
Bibliography:Application Number: CA20203161908