NOVEL VACCINE COMPOSITIONS FOR PORCINE EPIDEMIC DIARRHEA VIRUS AND PORCINE DELTACORONAVIRUS

The present invention is directed to novel immunogenic compositions that protect swine from disease caused by porcine epidemic diarrhea virus (PEDV). The present invention is also directed to novel immunogenic compositions that protect swine from disease caused by porcine deltacoronavirus (PDCoV), a...

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Main Authors PLAJA DILME, LAIA, BALASCH SANUY, MONICA, ROMERO GALINDO, OSCAR, DOMINOWSKI, PAUL J, CABANA SUMSI, MARTA, RAPP GABRIELSON, VICKI JON, URNIZA HOSTENCH, ALICIA, MARX, JACQUELINE GAYLE, HARDHAM, JOHN MORGAN
Format Patent
LanguageEnglish
Published 14.01.2016
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Summary:The present invention is directed to novel immunogenic compositions that protect swine from disease caused by porcine epidemic diarrhea virus (PEDV). The present invention is also directed to novel immunogenic compositions that protect swine from disease caused by porcine deltacoronavirus (PDCoV), alone or as combination vaccine to protect against PEDV. The compositions of the invention provide killed viruses whose effectiveness is enhanced by the selection of preferred adjuvants. Novel culture methods are also employed to increase reproducible yield of cultured viruses. Live vaccines are also provided from the Calafl4 PEDV isolate.
Bibliography:Application Number: CA20153161295