RAS INHIBITORS

The disclosure features macrocyclic compounds, and pharmaceutical compositions and protein complexes thereof, capable of inhibiting Ras proteins, and their uses in the treatment of cancers. L'invention concerne des composés macrocycliques, des compositions pharmaceutiques et des complexes proté...

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Main Authors CREGG, JAMES, BUCKL, ANDREAS, PITZEN, JENNIFER, KOLTUN, ELENA S, BURNETT, G. LESLIE, LIU, YANG, AGGEN, JAMES, KNOX, JOHN E, GILL, ADRIAN L, AAY, NAING, WHALEN, DANIEL M
Format Patent
LanguageEnglish
French
Published 14.05.2021
Subjects
CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:The disclosure features macrocyclic compounds, and pharmaceutical compositions and protein complexes thereof, capable of inhibiting Ras proteins, and their uses in the treatment of cancers. L'invention concerne des composés macrocycliques, des compositions pharmaceutiques et des complexes protéiques de ceux-ci, capables d'inhiber les protéines Ras, et leurs utilisations dans le traitement de cancers.
Bibliography:Application Number: CA20203160142