HETEROCYCLIC COMPOUNDS AS MODULATORS OF STIMULATOR OF INTERFERON GENES (STING)

The present invention relates to compounds of formula (I) and salts, stereoisomers, tautomers or N-oxides thereof that are useful as modulators of STING (Stimulator of Interferon Genes). The present invention further relates to the compounds of formula (I) for use as a medicament and to a pharmaceut...

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Main Authors SYNAK, DAVID JORG, FABRITIUS, CHARLES-HENRY, CWIERTNIA, GRZEGORZ WOJCIECH, MAHAJAN, TUSHAR RAVINDRA, LES, MARCIN WOJCIECH, ZUCHOWICZ, KAROL, TANGIRALA, SUNDARA RAGHURAM, DUDEK, LUKASZ PIOTR, ROGACKI, MACIEJ KRZYSZTOF, WRONOWSKI, MAREK, GIBAS, AGNIESZKA JUSTYNA, RADZIMIERSKI, ADAM, RAJDA, ANNA, ZAWADZKA, MAGDALENA IZABELA, STASI, LUIGI PIERO
Format Patent
LanguageEnglish
French
Published 17.06.2021
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:The present invention relates to compounds of formula (I) and salts, stereoisomers, tautomers or N-oxides thereof that are useful as modulators of STING (Stimulator of Interferon Genes). The present invention further relates to the compounds of formula (I) for use as a medicament and to a pharmaceutical composition comprising said compounds. La présente invention concerne des composés de formule (I) et des sels, des stéréoisomères, des tautomères ou des N-oxydes de ceux-ci qui sont utiles en tant que modulateurs de STING (stimulateur des gènes de l'interféron). La présente invention concerne en outre les composés de formule (I) destinés à être utilisés en tant que médicament et une composition pharmaceutique comprenant lesdits composés.
Bibliography:Application Number: CA20203159968