METHOD TO INDEPENDENTLY ANALYZE MULTIPLE BIOLOGICAL PROCESSES IN ENCAPSULATED 3D CELL CO-CULTURES

• Main Authors: PICARD, DIDIER, BOURRAT, BRYAN JOSUE, ROUX, AURELIEN, MOREAU, DIMITRI VINCENT, PEJOSKI, DAVID, SEGALA, GREGORY
• Format: Patent
• Language: English; French
• Published: 01.04.2021
• Subjects: APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; BEER; BIOCHEMISTRY; CHEMISTRY; COMPOSITIONS OR TEST PAPERS THEREFOR; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES; ENZYMOLOGY; INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES; MEASURING; MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS; METALLURGY; MICROBIOLOGY; MUTATION OR GENETIC ENGINEERING; PHYSICS; PROCESSES OF PREPARING SUCH COMPOSITIONS; SPIRITS; TESTING; VINEGAR; WINE

The invention relates to a multiplexed and encapsulated 3D cell co-culture drug testing or screening method. The invention also discloses an in vitro drug testing kit suitable for testing the effect of one or more drugs of interest on multiple biological processes in one or more target cell types. L'invention concerne un procédé de test ou de criblage de médicament de co-culture cellulaire 3D multiplexé et encapsulé. L'invention concerne également un kit de test de médicament in vitro approprié pour tester l'effet d'un ou de plusieurs médicaments d'intérêt sur de multiples processus biologiques dans un ou plusieurs types de cellules cibles.