3,6-DIAMINO-PYRIDAZIN-3-YL DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THEIR USES AS PRO-APOPTOTIC AGENTS

It is described a compounds of formula (I): a pharmaceutical composition comprising same, for use in the treatment of cancers, of diseases or conditions characterized by an excess or a deregulated activity of platelets. Also provided is the synthesis of intermediate Il est décrit des composés de for...

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Main Authors PARSONS, RACHEL JANE, MURRAY, JAMES BROOKE, DUNKEL, PETRA, RUDASOVA, MONIKA, MARAGNO, ANA LETICIA, NYERGES, MIKLOS, TIMARI, MATYAS PAL, NOVAK, TIBOR, HERNER, ANDRAS, MADARASZ, ZOLTAN, DODSWORTH, MARK PHILIP, SZIGETI, MARIANNA, WEBB, PAUL, COLLAND, FREDERIC, BEDFORD, SIMON, PACZAL, ATTILA, STROFEK, AGNES, CHANRION, MAIA, DAVIDSON, JAMES EDWARD PAUL, MOLNAR, MARK, STARCK, JEROME-BENOIT, DESOS, PATRICE, KOTSCHY, ANDRAS
Format Patent
LanguageEnglish
French
Published 04.02.2021
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Abstract It is described a compounds of formula (I): a pharmaceutical composition comprising same, for use in the treatment of cancers, of diseases or conditions characterized by an excess or a deregulated activity of platelets. Also provided is the synthesis of intermediate Il est décrit des composés de formule (I) : une composition pharmaceutique connexe à utiliser dans le traitement de cancers, de maladies ou de problèmes caractérisés par un excédent, ou une activité sans régulation, de plaquettes. Il est également décrit la synthèse d'intermédiaires.
AbstractList It is described a compounds of formula (I): a pharmaceutical composition comprising same, for use in the treatment of cancers, of diseases or conditions characterized by an excess or a deregulated activity of platelets. Also provided is the synthesis of intermediate Il est décrit des composés de formule (I) : une composition pharmaceutique connexe à utiliser dans le traitement de cancers, de maladies ou de problèmes caractérisés par un excédent, ou une activité sans régulation, de plaquettes. Il est également décrit la synthèse d'intermédiaires.
Author TIMARI, MATYAS PAL
MADARASZ, ZOLTAN
MURRAY, JAMES BROOKE
COLLAND, FREDERIC
MOLNAR, MARK
WEBB, PAUL
HERNER, ANDRAS
NYERGES, MIKLOS
DAVIDSON, JAMES EDWARD PAUL
DESOS, PATRICE
DODSWORTH, MARK PHILIP
STARCK, JEROME-BENOIT
PARSONS, RACHEL JANE
STROFEK, AGNES
PACZAL, ATTILA
BEDFORD, SIMON
DUNKEL, PETRA
RUDASOVA, MONIKA
NOVAK, TIBOR
SZIGETI, MARIANNA
KOTSCHY, ANDRAS
CHANRION, MAIA
MARAGNO, ANA LETICIA
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– fullname: TIMARI, MATYAS PAL
– fullname: NOVAK, TIBOR
– fullname: HERNER, ANDRAS
– fullname: MADARASZ, ZOLTAN
– fullname: DODSWORTH, MARK PHILIP
– fullname: SZIGETI, MARIANNA
– fullname: WEBB, PAUL
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– fullname: BEDFORD, SIMON
– fullname: PACZAL, ATTILA
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DocumentTitleAlternate DERIVES DE 3,6-DIAMINO-PYRIDAZIN-3-YLE, COMPOSITIONS PHARMACEUTIQUES LES CONTENANT ET LEURS UTILISATIONS EN TANT QU'AGENTS PRO-APOPTOTIQUES
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LES LABORATOIRES SERVIER
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Snippet It is described a compounds of formula (I): a pharmaceutical composition comprising same, for use in the treatment of cancers, of diseases or conditions...
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SubjectTerms CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
Title 3,6-DIAMINO-PYRIDAZIN-3-YL DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THEIR USES AS PRO-APOPTOTIC AGENTS
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