FC VARIANTS WITH ALTERED BINDING TO FCRN

The present application relates to a variant Fc of a human lgG Fc polypeptide, comprising a serine at position 434 and a glutamine at position 307, and the numbering is according to the EU index.

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Bibliographic Details
Main Authors KARKI, SHER BAHADUR, DESJARLAIS, JOHN RUDOLPH, LAZAR, GREGORY ALAN, CHAMBERLAIN, AARON, DAHIYAT, BASSIL
Format Patent
LanguageEnglish
French
Published 09.07.2009
Subjects
BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS THEREOF
CULTURE MEDIA
ENZYMOLOGY
FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
ORGANIC CHEMISTRY
PEPTIDES
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
SPIRITS
VINEGAR
WINE
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Summary:The present application relates to a variant Fc of a human lgG Fc polypeptide, comprising a serine at position 434 and a glutamine at position 307, and the numbering is according to the EU index.
Bibliography:Application Number: CA20083147069