A METHOD FOR THE PREPARATION OF A GEL-FORMING COMPOSITION

The current invention relates to a method for the preparation of a gel-forming composition for parenteral administration, said method comprises the steps of admixing a mixture of mammalian derived plasma and hyaluronic acid or a salt or ester thereof with a source of calcium, and wherein said calciu...

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Bibliographic Details
Main Authors ENA, SABRINA, ZEIPPEN, CAROLINE, BASTIANELLI, ENRICO, WINAND, JULIE
Format Patent
LanguageEnglish
French
Published 14.01.2021
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Summary:The current invention relates to a method for the preparation of a gel-forming composition for parenteral administration, said method comprises the steps of admixing a mixture of mammalian derived plasma and hyaluronic acid or a salt or ester thereof with a source of calcium, and wherein said calcium source is added to said mixture such that the calcium concentration is between 0.2 and 1.4 mg/ml. The invention also relates to a composition obtained by the method. La présente invention concerne un procédé de préparation d'une composition gélifiante pour une administration parentérale, ledit procédé comprenant les étapes consistant à mélanger un mélange de plasma dérivé de mammifère et d'acide hyaluronique ou d'un sel ou d'un ester de celui-ci avec une source de calcium, ladite source de calcium étant ajoutée audit mélange de sorte que la concentration en calcium soit comprise entre 0,2 et 1,4 mg/ml. L'invention concerne également une composition obtenue par le procédé.
Bibliography:Application Number: CA20203145854