TRICINE AND CITRIC ACID LIPIDS

Disclosed are cationic lipids which are compounds of Formula (A). Cationic lipids provided herein can be useful for delivery and expression of mRNA and encoded protein, e.g., as a component of liposomal delivery vehicle, and accordingly can be useful for treating various diseases, disorders and cond...

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Bibliographic Details
Main Authors KARVE, SHRIRANG, DEROSA, FRANK
Format Patent
LanguageEnglish
French
Published 24.12.2020
Subjects
ACYCLIC OR CARBOCYCLIC COMPOUNDS
BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS THEREOF
CULTURE MEDIA
ENZYMOLOGY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
SPIRITS
VINEGAR
WINE
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Summary:Disclosed are cationic lipids which are compounds of Formula (A). Cationic lipids provided herein can be useful for delivery and expression of mRNA and encoded protein, e.g., as a component of liposomal delivery vehicle, and accordingly can be useful for treating various diseases, disorders and conditions, such as those associated with deficiency of one or more proteins. L'invention concerne des lipides cationiques qui sont des composés de formule (A). Les lipides cationiques de la présente invention peuvent être utiles pour l'administration et l'expression d'ARNm et de protéine codée, par exemple, en tant que composant d'un véhicule d'administration liposomal, et peuvent par conséquent être utiles pour traiter diverses maladies et divers troubles et états, tels que ceux associés à une déficience en une ou plusieurs protéines.
Bibliography:Application Number: CA20203144457