ANTIBODY DRUG CONJUGATES HAVING LINKERS COMPRISING HYDROPHILIC GROUPS

Provided herein are linkers, linker-drug groups and antibody-drug conjugates comprising hydrophilic groups. L'invention concerne des lieurs, des groupes lieur-médicament et des conjugués anticorps-médicament comprenant des groupes hydrophiles.

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Bibliographic Details
Main Authors D'ALESSIO, JOSEPH ANTHONY, YU, BING, ZHANG, QIANG, MCNEILL, ERIC, NAKAJIMA, KATSUMASA, BURGER, MATTHEW T, CHEN, ZHUOLIANG, PALERMO, MARK G
Format Patent
LanguageEnglish
French
Published 26.11.2020
Subjects
CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:Provided herein are linkers, linker-drug groups and antibody-drug conjugates comprising hydrophilic groups. L'invention concerne des lieurs, des groupes lieur-médicament et des conjugués anticorps-médicament comprenant des groupes hydrophiles.
Bibliography:Application Number: CA20203140063