ALLOGENEIC CAR-T CELL, PREPARATION THEREFOR, AND APPLICATION THEREOF

Provided are allogeneic CAR-T cells prepared by expressing related functional proteins in T cells and regulating HLA class I molecules on the cell surface. Also provided is the use of the allogeneic CAR-T cells. L'invention concerne des cellules CAR-T allogéniques préparées par expression de pr...

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Main Authors HE, LING, QIN, HANXIAO, JIANG, YUCHEN, LIU, WEIKANG, XIA, YU, LI, JUN, ZHANG, PENGCHAO, XU, ZHAO
Format Patent
LanguageEnglish
French
Published 29.10.2020
Subjects
BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS THEREOF
CULTURE MEDIA
ENZYMOLOGY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
SPIRITS
VINEGAR
WINE
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Summary:Provided are allogeneic CAR-T cells prepared by expressing related functional proteins in T cells and regulating HLA class I molecules on the cell surface. Also provided is the use of the allogeneic CAR-T cells. L'invention concerne des cellules CAR-T allogéniques préparées par expression de protéines fonctionnelles associées dans des lymphocytes T et par régulation des molécules HLA de classe I sur la surface cellulaire. L'invention concerne également l'utilisation desdites cellules CAR-T allogéniques.
Bibliography:Application Number: CA20203137788