SUBSTITUTED POLYCYCLIC CARBOXYLIC ACIDS, ANALOGUES THEREOF, AND METHODS USING SAME

The present invention includes substituted polycyclic carboxylic acids, analogues thereof, and compositions comprising the same, which can be used to treat and/or prevent hepatitis B virus (HBV) infection and/or hepatitis D virus (HDV) in a patient. In certain embodiments, the invention provides a c...

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Main Authors QUINTERO, JORGE, COLE, ANDREW G, DORSEY, BRUCE D, FAN, YI, CHEN, SHUAI, KIRK, SHARON MARIE, GOTCHEV, DIMITAR B, SOFIA, MICHAEL J, KAKARLA, RAMESH
Format Patent
LanguageEnglish
French
Published 23.07.2020
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Summary:The present invention includes substituted polycyclic carboxylic acids, analogues thereof, and compositions comprising the same, which can be used to treat and/or prevent hepatitis B virus (HBV) infection and/or hepatitis D virus (HDV) in a patient. In certain embodiments, the invention provides a compound of formula (I), or a salt, solvate, geometric isomer, stereoisomer, tautomer, and any mixtures thereof. La présente invention concerne des acides carboxyliques polycycliques substitués, des analogues de ceux-ci, et des compositions les comprenant, lesquels peuvent être utilisés pour traiter et/ou prévenir une infection par le virus de l'hépatite B (HBV) et/ou le virus de l'hépatite D (VHD) chez un patient. Dans certains modes de réalisation, l'invention concerne un composé de formule (I), ou un sel, un solvate, un isomère géométrique, un stéréoisomère, un tautomère et des mélanges quelconques de ceux-ci.
Bibliography:Application Number: CA20203126102