NATIVE DELIVERY OF BIOMOLECULES INTO PLANT CELLS USING IONIC COMPLEXES WITH CELL-PENETRATING PEPTIDES

The invention relates to a complex comprising a first component: (i) a carrier peptide comprising a cell-penetrating sequence and a polycation sequence: and a second component (ii) a ribonucleic acid (RNA), PNA and/or protein, wherein the carrier peptide is a cyclic peptide comprising at least 2 cys...

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Main Authors RODRIGUEZ, MARIANELA, BAUER, JOERG, CARDOZA, VINITHA, BERNASCONI, PAUL, LAI, FANG-MING, NUMATA, KEIJI, GUO, BOYANG
Format Patent
LanguageEnglish
French
Published 25.06.2020
Subjects
BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS THEREOF
CULTURE MEDIA
ENZYMOLOGY
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
SPIRITS
VINEGAR
WINE
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Summary:The invention relates to a complex comprising a first component: (i) a carrier peptide comprising a cell-penetrating sequence and a polycation sequence: and a second component (ii) a ribonucleic acid (RNA), PNA and/or protein, wherein the carrier peptide is a cyclic peptide comprising at least 2 cysteine residues bridged by a disulphide bond. L'invention concerne un complexe comprenant un premier composant : (i) un peptide porteur comprenant une séquence de pénétration cellulaire et une séquence de polycations; et un second composant (ii) : un acide ribonucléique (ARN), un PNA et/ou une protéine, le peptide porteur étant un peptide cyclique comprenant au moins 2 résidus de cystéine pontés par une liaison disulfure.
Bibliography:Application Number: CA20193124395