ANTI-IGF-I RECEPTOR HUMANIZED ANTIBODY
Provided is a humanized antibody that, through IGF-I receptor, increases muscle mass but does not lower the blood glucose level. This humanized antibody: is an anti-IGF-I receptor humanized antibody, a fragment thereof, or a derivative thereof; has a specific amino acid sequence such as SEQ ID NOs:...
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Main Authors | , , , , , , , , , |
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Format | Patent |
Language | English French |
Published |
11.06.2020
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Subjects | |
Online Access | Get full text |
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Summary: | Provided is a humanized antibody that, through IGF-I receptor, increases muscle mass but does not lower the blood glucose level. This humanized antibody: is an anti-IGF-I receptor humanized antibody, a fragment thereof, or a derivative thereof; has a specific amino acid sequence such as SEQ ID NOs: 1 to 6 serving as a CDR sequence; and specifically binds to IGF-I receptor extracellular domain.
L'invention concerne un anticorps humanisé qui, par l'intermédiaire du récepteur de l'IGF-I, augmente la masse musculaire mais ne diminue pas le taux de glycémie. Cet anticorps humanisé : est un anticorps humanisé anti-récepteur de l'IGF-I, un fragment de celui-ci ou un dérivé de celui-ci; a une séquence d'acides aminés spécifique telle que les SEQ ID No. : 1 à 6 servant de séquence de CDR; et se lie spécifiquement au domaine extracellulaire du récepteur de l'IGF-I. |
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Bibliography: | Application Number: CA20193120740 |