MUCOADHESIVE GEL COMPOSITION

A pharmaceutical mucoadhesive gel composition for delivering therapeutic agents (such as progesterone) by buccal, nasal, vaginal and rectal administration, thereby avoiding the hepatic first-pass metabolism. The gel composition comprises a vehicle with a gel-forming agent and a bioadhesive agent; an...

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Bibliographic Details
Main Authors FIORE, SIMONA, BATES, OLIVER, BOLOGNA, WILLIAM, LARSEN, FINN, LOUVEL, LEA, BOUTIGNON, FRANCOIS
Format Patent
LanguageEnglish
French
Published 30.04.2020
Subjects
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:A pharmaceutical mucoadhesive gel composition for delivering therapeutic agents (such as progesterone) by buccal, nasal, vaginal and rectal administration, thereby avoiding the hepatic first-pass metabolism. The gel composition comprises a vehicle with a gel-forming agent and a bioadhesive agent; and a therapeutic agent dispersed or suspended in the vehicle. L'invention concerne une composition de gel mucoadhésif pharmaceutique destinée à administrer des agents thérapeutiques (tels que la progestérone) par administration buccale, nasale, vaginale et rectale, ce qui permet d'éviter le métabolisme du premier passage hépatique. La composition de gel comprend un véhicule avec un agent de formation de gel et un agent bioadhésif; et un agent thérapeutique dispersé ou suspendu dans le véhicule.
Bibliography:Application Number: CA20193117842