PHARMACEUTICAL DOSAGE FORM WHICH CAN BE ADMINISTERED ORALLY AND HAS MODIFIED RELEASE

The invention relates to pharmaceutical dosage forms, which can be administered orally and have a modified release and contain (3S)-3-(4-chloro-3-{[(2S,3R)-2-(4-chlorophenyl)-4,4,4-trifluoro-3-methylbutanoyl]amino}phenyl)-3-cyclopropylpropanoic acid, and to processes for preparing the dosage forms a...

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Bibliographic Details
Main Authors STROYER, ANKE, JACOBS, TIA, LOBBACK, CARMEN, SERNO, PETER
Format Patent
LanguageEnglish
French
Published 30.01.2020
Subjects
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:The invention relates to pharmaceutical dosage forms, which can be administered orally and have a modified release and contain (3S)-3-(4-chloro-3-{[(2S,3R)-2-(4-chlorophenyl)-4,4,4-trifluoro-3-methylbutanoyl]amino}phenyl)-3-cyclopropylpropanoic acid, and to processes for preparing the dosage forms and to the use thereof for treating and/or preventing diseases, in particular for treating and/or preventing cardiac, renal, pulmonary and ophthalmological disorders, disorders of the central nervous system, fibrotic and inflammatory disorders and metabolic diseases. L'invention concerne des formes galéniques pharmaceutiques à libération modifiée à administrer par voie orale contenant de l'acide (3S)-3-(4-chloro-3-{[(2S,3R)-2-(4-chlorophényl)-4,4,4-trifluoro-3- méthylbutanoyl]amino}phényl)-3-cyclopropylpropanoïque et des procédés de préparation des formes galéniques et leur utilisation pour traiter et/ou prévenir des maladies, notamment pour traiter et/ou prévenir des maladies cardiaques, rénales, pulmonaires et ophtalmologiques, des maladies du système nerveux central, des maladies fibrotiques et inflammatoires et des maladies métaboliques.
Bibliography:Application Number: CA20193107174