METHOD FOR INCREASING THE PRODUCTION OF AMINO ACIDS IN SUBMERGED CORYNEBACTERIUM CULTURE

Described are methods for improving the production of the amino acids glutamate and lysine in submerged Corynebacterium culture comprising adding to a submerged Corynebacterium culture a non- enzymatic fraction of spent Trichoderma fermentation broth, wherein the Corynebacterium grown in the presenc...

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Main Authors CAIMI, PERRY G, LEFEBVRE, BRIAN G, BRODERICK, LYNN GOODFELLOW, GRUBER, TANJA MARIA, REN, YIXIN
Format Patent
LanguageEnglish
French
Published 27.06.2019
Subjects
BEER
BIOCHEMISTRY
CHEMISTRY
ENZYMOLOGY
FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE
METALLURGY
MICROBIOLOGY
MUTATION OR GENETIC ENGINEERING
SPIRITS
VINEGAR
WINE
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Summary:Described are methods for improving the production of the amino acids glutamate and lysine in submerged Corynebacterium culture comprising adding to a submerged Corynebacterium culture a non- enzymatic fraction of spent Trichoderma fermentation broth, wherein the Corynebacterium grown in the presence of the non-enzymatic fraction of spent Trichoderma fermentation broth produce an increased amount of small molecules compared to Corynebacterium grown in an otherwise identical submerged culture in the absence of the non-enzymatic fraction of spent Trichoderma fermentation broth, wherein the increase in the production of the amino acids glutamate and lysine is not due to enzymatic activity in the spent Trichoderma fermentation broth. L'invention concerne des procédés permettant d'améliorer la production des acides aminés glutamate et lysine dans une culture immergée de Corynebacterium, consistant à ajouter, à une culture immergée de Corynebacterium, une fraction non enzymatique de bouillon de fermentation de Trichoderma épuisé. Les Corynebacterium cultivées en présence de la fraction non enzymatique du bouillon de fermentation de Trichoderma épuisé produisent une quantité accrue de petites molécules par rapport aux Corynebacterium cultivées dans une culture immergée par ailleurs identique en l'absence de la fraction non enzymatique du bouillon de fermentation de Trichoderma épuisé ; l'augmentation de la production des acides aminés glutamate et lysine n'est pas due à l'activité enzymatique dans le bouillon de fermentation de Trichoderma épuisé.
Bibliography:Application Number: CA20183086341