COMPOUNDS AND USE THEREOF IN THE EXPANSION OF STEM CELLS AND/OR PROGENITOR CELLS

• Main Authors: MARINIER, ANNE, SAUVAGEAU, GUY, CHANTIGNY, YVES, SIMONEAU, BRUNO, YEH, JONATHAN
• Format: Patent
• Language: English; French
• Published: 09.05.2019
• Subjects: BEER; BIOCHEMISTRY; CHEMISTRY; COMPOSITIONS THEREOF; CULTURE MEDIA; ENZYMOLOGY; HETEROCYCLIC COMPOUNDS; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; METALLURGY; MICROBIOLOGY; MICROORGANISMS OR ENZYMES; MUTATION OR GENETIC ENGINEERING; ORGANIC CHEMISTRY; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS; SPIRITS; VINEGAR; WINE

The invention relates to compounds of formula I and pharmaceutical compositions containing them. Also, the invention relates to methods for expanding stem cells and/or progenitor cells and methods for treating a hematopoietic disorder/malignancy, and autoimmune disease and/or an inherited immunodeficient disease (I). La présente invention concerne des composés de formule I et des compositions pharmaceutiques les contenant. L'invention concerne également des procédés d'expansion de cellules souches et/ou de cellules progénitrices et des méthodes de traitement d'un trouble/malignité hématopoïétique, et d'une maladie auto-immune et/ou d'une maladie immunodéficiente héritée (I).