PYRIDINE CARBONYL DERIVATIVES AND THERAPEUTIC USES THEREOF AS TRPC6 INHIBITORS

The invention relates to compounds of formula (I), and pharmaceutically acceptable salts thereof, wherein R1 to R7, A, Y and L are as defined herein. The invention also relates to pharmaceutical compositions comprising these compounds, methods of using these compounds in the treatment of various dis...

Full description

Saved in:
Bibliographic Details
Main Authors GOTTSCHLING, DIRK, SURPRENANT, SIMON, SARKO, CHRISTOPHER RONALD, RAZAVI, HOSSEIN, LOWE, MICHAEL D, HEINE, NIKLAS, WU, XINYUAN, SMITH KEENAN, LANA LOUISE, TURNER, MICHAEL ROBERT, TAKAHASHI, HIDENORI, BOUYSSOU, THIERRY
Format Patent
LanguageEnglish
French
Published 02.05.2019
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
Online AccessGet full text

Cover

More Information
Summary:The invention relates to compounds of formula (I), and pharmaceutically acceptable salts thereof, wherein R1 to R7, A, Y and L are as defined herein. The invention also relates to pharmaceutical compositions comprising these compounds, methods of using these compounds in the treatment of various diseases and disorders, processes for preparing these compounds and intermediates useful in these processes. La présente invention concerne des composés représentés par la formule (I), et des sels pharmaceutiquement acceptables de ceux-ci. Dans la formule, R1 à R7, A, Y et L sont tels que définis dans la description. L'invention concerne également des compositions pharmaceutiques contenant ces composés, des procédés d'utilisation de ces composés pour traiter différents troubles et maladies, ainsi que des procédés de préparation de ces composés et des intermédiaires utilisés dans ces procédés.
Bibliography:Application Number: CA20183078769