COMBINATION TREATMENT FOR CANCER

Disclosed herein is a method of treating cancer, such as multiple myeloma, involving the combination of an anti-BCMA antigen binding protein (e.g., an anti-BCMA antibody) and an immunomodulatory drug (e.g. pomalidomide or lenalidomide). The combinations can also include an anti-inflammatory compound...

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Bibliographic Details
Main Authors OPALINSKA, JOANNA, MAYES, PATRICK, KHANDEKAR, SANJAY
Format Patent
LanguageEnglish
French
Published 21.03.2019
Subjects
CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:Disclosed herein is a method of treating cancer, such as multiple myeloma, involving the combination of an anti-BCMA antigen binding protein (e.g., an anti-BCMA antibody) and an immunomodulatory drug (e.g. pomalidomide or lenalidomide). The combinations can also include an anti-inflammatory compound (e.g. dexamethasone). L'invention concerne une méthode de traitement du cancer, tel que le myélome multiple, impliquant la combinaison d'une protéine de liaison à l'antigène anti-BCMA (par exemple un anticorps anti-BCMA) et d'un médicament immunomodulateur (par exemple le pomalidomide ou le lénalidomide). Ces combinaisons peuvent également comprendre un composé anti-inflammatoire (par exemple la dexaméthasone).
Bibliography:Application Number: CA20183075716