MODIFIED NUCLEOTIDES FOR SYNTHESIS OF NUCLEIC ACIDS, A KIT CONTAINING SUCH NUCLEOTIDES AND THEIR USE FOR THE PRODUCTION OF SYNTHETIC NUCLEIC ACID SEQUENCES OR GENES

• Main Authors: YBERT, THOMAS, GARIEL, SYLVAIN
• Format: Patent
• Language: English; French
• Published: 16.11.2021
• Subjects: BEER; BIOCHEMISTRY; CHEMISTRY; COMPOSITIONS OR TEST PAPERS THEREFOR; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES; DERIVATIVES THEREOF; ENZYMOLOGY; FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE; MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS; METALLURGY; MICROBIOLOGY; MUTATION OR GENETIC ENGINEERING; NUCLEIC ACIDS; NUCLEOSIDES; NUCLEOTIDES; ORGANIC CHEMISTRY; PROCESSES OF PREPARING SUCH COMPOSITIONS; SPIRITS; SUGARS; VINEGAR; WINE

Modified nucleotide, for the synthesis of enzymatic long-chain nucleic acids, comprised of a natural nitrogen base, a ribose or deoxyribose carbohydrate, and at least one phosphate grouping, characterized in that it comprises at least one R grouping, called modifier grouping, range: - by said R nitrogen base comprised of at least one functional terminal grouping, the nucleotide presenting itself under the following formula (III): (see formula III) Nucléotide modifié, destiné à la synthèse d'acides nucléiques à longues chaînes par voie enzymatique, comprenant une base azotée naturelle , un glucide ribose ou désoxyribose, et au moins un groupement phosphate, caractérisé en ce qu'il comprend au moins un groupement R, dénommé groupement modificateur, porté: - par ladite base azotée R comprenant au moins un groupement terminal fonctionnel, le nucléotide se présentant sous la forme de la formule (III) suivante : (see formula III)