IMMUNE-CELL TARGETED BISPECIFIC CHIMERIC PROTEINS AND USES THEREOF

The present invention relates, in part, to targeted chimeric proteins with beneficial therapeutic effects, including, for example, effects mediated by chimeric proteins which comprise modified signaling agents two or more targeting moieties. Methods of treatment and pharmaceutical compositions compr...

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Bibliographic Details
Main Authors VAN DER HEYDEN, JOSE, UZE, GILLES, GARCIN, GENEVIEVE, TAVERNIER, JAN, BORDAT, YANN
Format Patent
LanguageEnglish
French
Published 16.08.2018
Subjects
CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Summary:The present invention relates, in part, to targeted chimeric proteins with beneficial therapeutic effects, including, for example, effects mediated by chimeric proteins which comprise modified signaling agents two or more targeting moieties. Methods of treatment and pharmaceutical compositions comprising the chimeric proteins are also provided. The present invention finds use in the treatment of various disease and disorders. La présente invention concerne en partie des protéines chimères ciblées présentant des effets thérapeutiques avantageux, comprenant par exemple des effets médiés par des protéines chimères qui comprennent des agents modifiés de signalisation de deux fragments de ciblage, ou plus. L'invention concerne également des méthodes de traitement et des compositions pharmaceutiques comprenant les protéines chimères. La présente invention trouve une utilisation dans le traitement de différents troubles et maladies.
Bibliography:Application Number: CA20183050601