ANTI-BCMA HEAVY CHAIN-ONLY ANTIBODIES

Anti-BCMA heavy chain-only antibodies (HCAb) and disclosed, along with methods of making such antibodies, compositions, including pharmaceutical compositions, comprising such antibodies, and their use to treat B-cell disorders characterized by the expression of BCMA. L'invention concerne des an...

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Bibliographic Details
Main Authors HARRIS, KATHERINE E, VAN SCHOOTEN, WIM, TRINKLEIN, NATHAN, DANG, KEVIN, ALDRED, SHELLEY FORCE
Format Patent
LanguageEnglish
French
Published 28.06.2018
Subjects
CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:Anti-BCMA heavy chain-only antibodies (HCAb) and disclosed, along with methods of making such antibodies, compositions, including pharmaceutical compositions, comprising such antibodies, and their use to treat B-cell disorders characterized by the expression of BCMA. L'invention concerne des anticorps à chaîne lourde uniquement anti-BCMA (HCAb) et des procédés de préparation de tels anticorps, des compositions, y compris des compositions pharmaceutiques, comprenant de tels anticorps, et leur utilisation pour traiter des troubles de lymphocytes B caractérisés par l'expression de BCMA.
Bibliography:Application Number: CA20173047419