ALPHA(V)BETA(6) INTEGRIN-BINDING PEPTIDES AND METHODS OF USE THEREOF
The present invention provides peptide conjugates that target an integrin such as avß6 integrin. In particular embodiments, the peptide conjugates comprise a moiety such as a PEG moiety, an imaging agent, or a therapeutic agent. The peptide conjugates of the present invention are particularly useful...
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| Main Authors | , |
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| Format | Patent |
| Language | English French |
| Published |
21.12.2017
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| Subjects | |
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| Abstract | The present invention provides peptide conjugates that target an integrin such as avß6 integrin. In particular embodiments, the peptide conjugates comprise a moiety such as a PEG moiety, an imaging agent, or a therapeutic agent. The peptide conjugates of the present invention are particularly useful for imaging a tumor, organ, or tissue. Compositions and kits containing the peptide conjugates of the present invention are also provided herein.
La présente invention concerne des conjugués peptidiques qui ciblent une intégrine telle quE l'intégrine ?ß6. Dans des modes de réalisation particuliers, les conjugués peptidiques comprennent une fraction telle qu'une fraction PEG, un agent d'imagerie ou un agent thérapeutique. Les conjugués peptidiques de la présente invention sont particulièrement utiles pour l'imagerie d'une tumeur, d'un organe ou d'un tissu. L'invention concerne également des compositions et des kits contenant les conjugués peptidiques de l'invention. |
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| AbstractList | The present invention provides peptide conjugates that target an integrin such as avß6 integrin. In particular embodiments, the peptide conjugates comprise a moiety such as a PEG moiety, an imaging agent, or a therapeutic agent. The peptide conjugates of the present invention are particularly useful for imaging a tumor, organ, or tissue. Compositions and kits containing the peptide conjugates of the present invention are also provided herein.
La présente invention concerne des conjugués peptidiques qui ciblent une intégrine telle quE l'intégrine ?ß6. Dans des modes de réalisation particuliers, les conjugués peptidiques comprennent une fraction telle qu'une fraction PEG, un agent d'imagerie ou un agent thérapeutique. Les conjugués peptidiques de la présente invention sont particulièrement utiles pour l'imagerie d'une tumeur, d'un organe ou d'un tissu. L'invention concerne également des compositions et des kits contenant les conjugués peptidiques de l'invention. |
| Author | TANG, YNG SUTCLIFFE, JULIE L |
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| DocumentTitleAlternate | PEPTIDES DE LIAISON A L'INTEGRINE ALPHA (V) BETA (6) ET LEURS PROCEDES D'UTILISATION |
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| Snippet | The present invention provides peptide conjugates that target an integrin such as avß6 integrin. In particular embodiments, the peptide conjugates comprise a... |
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| SubjectTerms | CHEMISTRY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES |
| Title | ALPHA(V)BETA(6) INTEGRIN-BINDING PEPTIDES AND METHODS OF USE THEREOF |
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