PROCESSES AND COMPOSITIONS FOR METHYLATION-BASED ENRICHMENT OF FETAL NUCLEIC ACID FROM A MATERNAL SAMPLE USEFUL FOR NON-INVASIVE PRENATAL DIAGNOSES

Provided are compositions and processes that utilize genomic regions that are differentially methylated between a mother and her fetus to separate, isolate or enrich fetal nucleic acid from a maternal sample. The compositions and processes described herein are particularly useful for non-invasive pr...

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Bibliographic Details
Main Authors EHRICH, MATHIAS, JENSEN, TAYLOR JACOB, NYGREN, ANDERS OLOF HERMAN
Format Patent
LanguageEnglish
French
Published 27.07.2021
Subjects
BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS OR TEST PAPERS THEREFOR
CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES
ENZYMOLOGY
MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS
METALLURGY
MICROBIOLOGY
MUTATION OR GENETIC ENGINEERING
PROCESSES OF PREPARING SUCH COMPOSITIONS
SPIRITS
VINEGAR
WINE
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Summary:Provided are compositions and processes that utilize genomic regions that are differentially methylated between a mother and her fetus to separate, isolate or enrich fetal nucleic acid from a maternal sample. The compositions and processes described herein are particularly useful for non-invasive prenatal diagnostics, including the detection of chromosomal aneuplodies. Des compositions et des procédés utilisent des régions génomiques dont la méthylation est différente entre une mère et son ftus afin de séparer, disoler ou denrichir un échantillon maternel en acide nucléique ftal. Les compositions et les procédés décrits ici sont particulièrement utiles pour les diagnostics prénatals non invasifs, notamment la détection daneuploïdies chromosomiques.
Bibliography:Application Number: CA20103024967