ENGINEERED POLYPEPTIDE CONJUGATES
The present invention provides engineered polypeptide conjugates (e.g., antibody-drug-conjugates) comprising specific acyl donor glutamine-containing tags and amine donor agents. The invention also provides methods of making such engineered polypeptide conjugates using transglutaminase and methods o...
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Format | Patent |
Language | English French |
Published |
05.02.2015
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Online Access | Get full text |
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Abstract | The present invention provides engineered polypeptide conjugates (e.g., antibody-drug-conjugates) comprising specific acyl donor glutamine-containing tags and amine donor agents. The invention also provides methods of making such engineered polypeptide conjugates using transglutaminase and methods of using thereof. |
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AbstractList | The present invention provides engineered polypeptide conjugates (e.g., antibody-drug-conjugates) comprising specific acyl donor glutamine-containing tags and amine donor agents. The invention also provides methods of making such engineered polypeptide conjugates using transglutaminase and methods of using thereof. |
Author | FARIAS, SANTIAGO ESTEBAN GALINDO CASAS, MERITXELL STROP, PAVEL |
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DocumentTitleAlternate | CONJUGUES DE POLYPEPTIDES MODIFIES |
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RelatedCompanies | RINAT NEUROSCIENCE CORP |
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Snippet | The present invention provides engineered polypeptide conjugates (e.g., antibody-drug-conjugates) comprising specific acyl donor glutamine-containing tags and... |
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Title | ENGINEERED POLYPEPTIDE CONJUGATES |
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