ENGINEERED POLYPEPTIDE CONJUGATES

The present invention provides engineered polypeptide conjugates (e.g., antibody-drug-conjugates) comprising specific acyl donor glutamine-containing tags and amine donor agents. The invention also provides methods of making such engineered polypeptide conjugates using transglutaminase and methods o...

Full description

Saved in:
Bibliographic Details
Main Authors STROP, PAVEL, FARIAS, SANTIAGO ESTEBAN, GALINDO CASAS, MERITXELL
Format Patent
LanguageEnglish
French
Published 05.02.2015
Subjects
CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
Online AccessGet full text

Cover

Abstract The present invention provides engineered polypeptide conjugates (e.g., antibody-drug-conjugates) comprising specific acyl donor glutamine-containing tags and amine donor agents. The invention also provides methods of making such engineered polypeptide conjugates using transglutaminase and methods of using thereof.
AbstractList The present invention provides engineered polypeptide conjugates (e.g., antibody-drug-conjugates) comprising specific acyl donor glutamine-containing tags and amine donor agents. The invention also provides methods of making such engineered polypeptide conjugates using transglutaminase and methods of using thereof.
Author FARIAS, SANTIAGO ESTEBAN
GALINDO CASAS, MERITXELL
STROP, PAVEL
Author_xml – fullname: STROP, PAVEL
– fullname: FARIAS, SANTIAGO ESTEBAN
– fullname: GALINDO CASAS, MERITXELL
BookMark eNrjYmDJy89L5WRQdPVz9_RzdQ1ydVEI8PeJDHANCPF0cVVw9vfzCnV3DHEN5mFgTUvMKU7lhdLcDApuriHOHrqpBfnxqcUFicmpeakl8c6OxgaGRpaWJo6GxkQoAQDA0iOc
ContentType Patent
DBID EVB
DatabaseName esp@cenet
DatabaseTitleList
Database_xml – sequence: 1
  dbid: EVB
  name: esp@cenet
  url: http://worldwide.espacenet.com/singleLineSearch?locale=en_EP
  sourceTypes: Open Access Repository
DeliveryMethod fulltext_linktorsrc
Discipline Medicine
Chemistry
Sciences
DocumentTitleAlternate CONJUGUES DE POLYPEPTIDES MODIFIES
ExternalDocumentID CA3012994A1
GroupedDBID EVB
ID FETCH-epo_espacenet_CA3012994A13
IEDL.DBID EVB
IngestDate Fri Jul 19 12:45:56 EDT 2024
IsOpenAccess true
IsPeerReviewed false
IsScholarly false
Language English
French
LinkModel DirectLink
MergedId FETCHMERGED-epo_espacenet_CA3012994A13
Notes Application Number: CA20143012994
OpenAccessLink https://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20150205&DB=EPODOC&CC=CA&NR=3012994A1
ParticipantIDs epo_espacenet_CA3012994A1
PublicationCentury 2000
PublicationDate 20150205
PublicationDateYYYYMMDD 2015-02-05
PublicationDate_xml – month: 02
  year: 2015
  text: 20150205
  day: 05
PublicationDecade 2010
PublicationYear 2015
RelatedCompanies RINAT NEUROSCIENCE CORP
RelatedCompanies_xml – name: RINAT NEUROSCIENCE CORP
Score 2.975539
Snippet The present invention provides engineered polypeptide conjugates (e.g., antibody-drug-conjugates) comprising specific acyl donor glutamine-containing tags and...
SourceID epo
SourceType Open Access Repository
SubjectTerms CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
Title ENGINEERED POLYPEPTIDE CONJUGATES
URI https://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20150205&DB=EPODOC&locale=&CC=CA&NR=3012994A1
hasFullText 1
inHoldings 1
isFullTextHit
isPrint
link http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwY2BQAdaJZsZmKYm6qWYmwA6KpWGSbpKlYbKuiWlKimFKShKwjgOvtvAz8wg18YowjWBiyITthQGfE1oOPhwRmKOSgfm9BFxeFyAGsVzAayuL9ZMygUL59m4hti5q0N4xsHVjZGCq5uJk6xrg7-LvrObsbOvsqOYXZGsMGnCxNHEEdpRYQa1o0DH7rmFOoE0pBcg1ipsgA1sA0LC8EiEGptQ8YQZOZ9jFa8IMHL7Q-W4gE5r1ikUYFGFHQLm6KAT4-0QGuAaEeLq4Kjj7-3mFujuGuAaLMii4uYY4e-gC7YqH-yve2RHuKmMxBhZgdz9VgkHBPNk8ySApycIg2cjYJBnYfgGGZaKRhUFqIsjZhsaSDJI4jZHCIyfNwAUKIPCKY1MZBpaSotJUWWCFWpIkBw4KACQMdUQ
link.rule.ids 230,309,786,891,25594,76903
linkProvider European Patent Office
linkToHtml http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwfV3dT4MwEL8s0zjfdGrc_MLE8EaE8TUeiGEtyCYDoszMJ0KBh73MxWH89z0amL7oW9Mm1_aS6-9-7d0V4A4x0VCNIpNKQ0OCYilMYpaSS5peFEpRMMQ4Hm0RGv5Cmy31ZQdWbS4MrxP6xYsjokXlaO8VP683P5dYlMdWbu_ZCrveH7zEpmLDjtG7Gcm6SCe2G0c0IiIhNnHE8NlW6wsXS3OQKO2ZyAg5U3qd1Ekpm9-I4h3BfozC1tUxdMp1H3qk_XitDwfz5r0bm43pbU_gti0B5VIhjoK32I2TKXUFEoWzxaOTuC-nIHhuQnwJ50p3-0qJs1uVegZdpPvlOQhmbjKZsbGcj1QtR_8FdZmNxnKZofOPkDOAwZ9ihv-M3UDPT-ZBGkzDpws4rJXFo4_1S-hWH5_lFYJrxa65Wr4BxG94Lg
openUrl ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Apatent&rft.title=ENGINEERED+POLYPEPTIDE+CONJUGATES&rft.inventor=STROP%2C+PAVEL&rft.inventor=FARIAS%2C+SANTIAGO+ESTEBAN&rft.inventor=GALINDO+CASAS%2C+MERITXELL&rft.date=2015-02-05&rft.externalDBID=A1&rft.externalDocID=CA3012994A1