ENGINEERED POLYPEPTIDE CONJUGATES
The present invention provides engineered polypeptide conjugates (e.g., antibody-drug-conjugates) comprising specific acyl donor glutamine-containing tags and amine donor agents. The invention also provides methods of making such engineered polypeptide conjugates using transglutaminase and methods o...
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Main Authors | , , |
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Format | Patent |
Language | English French |
Published |
05.02.2015
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Subjects | |
Online Access | Get full text |
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Summary: | The present invention provides engineered polypeptide conjugates (e.g., antibody-drug-conjugates) comprising specific acyl donor glutamine-containing tags and amine donor agents. The invention also provides methods of making such engineered polypeptide conjugates using transglutaminase and methods of using thereof. |
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Bibliography: | Application Number: CA20143012994 |